Use of Probiotics and Prebiotics in the Treatment of Intestinal Diseases

  • BlogBlog
  • 24 August 2023

Did you know that in my scientific research as a microbiome microbiologist for over 25 years, the first issue I often observe in individuals with intestinal diseases is intestinal dysbiosis?

Dysbiosis refers to an imbalance in the bacterial composition within the gut. Conditions like Crohn's disease and Ulcerative Colitis, Irritable Bowel Syndrome (IBS), diverticulitis, anal fissures, chronic constipation and diarrhea, allergies, asthma, psoriasis, rheumatoid arthritis, obesity, diabetes, cancer, and many other diseases are fundamentally linked to disrupted bacterial balance or disbiosis.

In individuals battling intestinal diseases, the most common problem I encounter is the complete deterioration of their quality of life. As individuals struggle to even perform daily tasks, their homes, families, and relationships are affected, leading to social isolation, depression, anxiety, and an increasing sense of loneliness. When gut health deteriorates, the brain is impacted. Anxiety and panic disorders persist in the brain, further influencing the gut's equilibrium. This situation underscores the significance of the brain-gut axis and results in a vicious cycle.

Let me remind you of a sentence you've likely heard many times before. As you know, serotonin, often referred to as the "happiness hormone," is produced about 90% in the intestines. This proportion is undeniably significant. Studies in the field of neurogastroenterology have shown the interaction between the gastrointestinal system and the central nervous system. The intestines play a major role in a person's overall mental well-being, influencing conditions such as anxiety, panic disorders, and more, alongside the brain. To think clearly and overcome mental health symptoms like foggy thinking, anxiety, depression, and mood fluctuations, you must prioritize your intestines. A person's gut microbiota can change and be disrupted due to genetic factors, birth method, antibiotic usage, stress, environmental influences, infections, and aging. In our research, we have repeatedly observed that the use of probiotics and prebiotics reduces and eliminates the imbalances and disruptions in the intestines.

Formulated and developed by scientists, probiotics consisting of bacteria that can coexist harmoniously and the prebiotics that make up their nourishment have a wide range of benefits, from inflammatory bowel diseases to IBS, diabetes, osteoporosis, and urogenital disease treatment. Lastly, I'd like to mention that the use of probiotics and prebiotics in intestinal diseases increases the production of intestinal mucosal secretions in the largest mucosal surface of the body, the intestinal epithelium, reducing gut permeability and positively affecting the brain-gut axis by enhancing the production of short-chain fatty acids (SCFAs) responsible for releasing gut hormones.

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