Ali Rıza Akın
The trillions of bacteria in our bodies shape not only our stomach but our entire health. One of the brightest stars in this micro world is Akkermansia muciniphila. This bacterium, which strengthens the intestinal wall, shows promise in many areas from weight problems to diabetes.
What is Akkermansia Probiotic and How Does It Work?
Akkermansia muciniphila, an anaerobic bacterium living in the mucus layer of the large intestine, takes its name from its Latin origin meaning "mucin lover." Unlike classic probiotics, it does not feed on the foods we eat; it lives with the intestine's own protective mucus layer.
This process is not frightening; on the contrary, it is a clever cycle: While Akkermansia cleans out old mucus, it encourages intestinal cells to produce a new and thicker layer. The result? The intestinal wall becomes an impregnable fortress against harmful substances.
https://pmc.ncbi.nlm.nih.gov/articles/PMC11297771/
Strengthens the Gut Barrier (Anti-Leaky Gut)
The intestinal wall is the body's most important line of defense; it decides what will enter the bloodstream. This is where Akkermansia comes into play: By thickening the mucus layer, it prevents toxins, allergens, and pathogens from leaking through.
Research shows that a deficiency of this bacterium leads to "leaky gut" syndrome; which triggers chronic fatigue, joint pain, and autoimmune disorders. A strong mucus layer protects the body from the inside.
https://pmc.ncbi.nlm.nih.gov/articles/PMC11297771/
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.00645/full
Provides Natural Weight Management
The level of Akkermansia in the intestines of obese individuals is usually very low; whereas it is abundant in those of healthy weight. This bacterium increases satiety hormones (especially GLP-1) secreted from the gut, curbing appetite and slowing the growth of fat cells.
Animal and human studies prove that diet-enriched Akkermansia supports weight loss. It especially targets dangerous fat accumulation in the abdominal area.
https://www.pnas.org/doi/10.1073/pnas.1219451110
Increases Insulin Sensitivity (Diabetes Support)
Insulin resistance, one of the greatest enemies of modern life, disrupts sugar metabolism. Akkermansia plays a major role here: It regulates glucose utilization and improves the pancreas's response to insulin.
Clinical trials reveal that this probiotic balances blood sugar in people with Type 2 diabetes; the effect is especially pronounced in those with high initial levels.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8373164/
https://www.sciencedirect.com/science/article/abs/pii/S1550413124004923
Suppresses Chronic Inflammation
Low-grade inflammation is at the root of many diseases, from heart attack to brain fog. Akkermansia calms immune cells, extinguishing this unnecessary fire. While repairing the gut barrier, it reduces inflammation markers (such as CRP) throughout the body.
Long-term studies indicate that this effect reduces the risk of Alzheimer's and cancer.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10873422/
Triggers GLP-1 Hormone Naturally
While popular weight loss drugs of recent years mimic GLP-1 agonists, Akkermansia enables the body to do this on its own. The bacterium stimulates GLP-1 secretion from intestinal cells – providing both satiety and sugar control.
Scientific data confirm that Akkermansia extracts directly increase this hormone.
https://pubmed.ncbi.nlm.nih.gov/33820962/
Which Foods Increase Akkermansia?
It is not naturally found in fermented foods, but you can increase it with the right nutrition:
- Polyphenols: Pomegranate, blueberry, black grape – an antioxidant feast.
- Prebiotics: Onion, garlic, Jerusalem artichoke – a fiber fuel depot.
- Healthy Fats: Olive oil, salmon – optimizes the environment.
- Beverages: Green tea, filtered coffee – polyphenol support.
- Lifestyle: Intermittent fasting enables Akkermansia to switch to "cleaning mode."
https://natashathomasmd.com/the-benefits-of-akkermansia-and-its-role-in-metabolic-health/
Microbiota Revolution in Turkey: Ali Rıza Akın and Next Microbiome
Groundbreaking studies in the field of gut microbiota in Turkey are making waves in the world of biotechnology. Biologist Ali Rıza Akın, with nearly 25 years of microbiota research experience, brings a Silicon Valley-standard vision to Turkey as the founder and chief scientific officer (CSO) of Next Microbiome. The SIMS (Stool inVivo Mimicking System) technology developed under Akın's leadership directly mimics the gut ecosystem in the laboratory based on human stool – with real intestinal features such as oxygen level, pH balance, and nutrient flow.
Thanks to this innovative system, they can directly measure with which foods and under what conditions Akkermansia muciniphila proliferates best. Going beyond the classic probiotic "throw it in and let it collide" approach, Next Microbiome designs formulas by simulating how bacteria behave in real life. The result? Next-generation products that repair the gut barrier from within and reset metabolism.
Probiome-NOVO: A Science-Based Akkermansia-Focused Solution
Next Microbiome's star product Probiome-NOVO is a "gut architect" supported by Ali Rıza Akın's patented technologies. This supplement not only nourishes Akkermansia; by accelerating its mucus renewal cycle, it offers a fundamental solution to problems such as leaky gut, insulin resistance, and chronic inflammation. A similar formula sold in the US market under the name Boost Synergy GLP-1 stands out in weight management and diabetes control by naturally triggering the GLP-1 hormone.
Shaped by Akın's philosophy "Live as long as your bacteria", these products are far from random supplements; they are approaches validated by clinical data. The SIMS model pre-tests the effect of each formula on the intestinal wall – thus, efficacy is guaranteed.
Why Does Next Microbiome Make a Difference?
- Local but global vision: Technologies produced in Turkey meet international standards.
- Personalized microbiota: Instead of classic yogurt probiotics, solutions tailored to your gut type.
- Investment in the future: Targeting keystone bacteria like Akkermansia for long-term health gains.
Instead of leaving your health to chance and traditional methods, trust this approach supported by scientific data. Ali Rıza Akın and Next Microbiome are preparing your gut for the future. The revolution that starts with a single bacterium can transform your entire life. Start discovering your microbiota with Next Microbiome!
